Professor and Director of Lombardi Comprehensive Cancer Center
Francis L. and Charlotte G. Gragnani Chair, Department of Oncology
Lombardi Comprehensive Cancer Center
202-687-2110
weinerl@georgetown.edu
Georgetown
Profile
Louis M. Weiner is an internationally recognized medical oncologist specializing in the
treatment in gastrointestinal cancers. He is also an
accomplished researcher developing novel immunotherapy treatments in his
laboratory. Dr. Weiner was named director of the Lombardi Comprehensive
Cancer Center on October 16, 2007.
Dr. Weiner is recognized for his laboratory and clinical research
focusing on new therapeutic approaches that mobilize the patient's
immune system to fight cancer using monoclonal antibodies -
laboratory-crafted proteins designed to recognize specific cancer cells.
His laboratory designs and produces new antibody-based proteins with
the aim of improving their tumor-targeting and immune-stimulating
properties. This research has led to the surprising and clinically
important observation that tumor targeting is impaired if the antibodies
attach too tightly to their tumor targets. Dr. Weiner has also
developed, and has clinically tested, "bispecific" antibodies and
related antibody-based proteins designed not only to recognize and bind
to cancer cells but also to stimulate immune-system cells to attack the
targeted cancer cells.